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1

Design and synthesis of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, a novel and highly active inhibitor of nitric oxide production in mouse macrophages

Tadashi Honda, BarbieAnn V. Rounds, Gordon W. Gribble, Nanjoo Suh, Yongping Wang, Michael B. Sporn

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 222 KB

english, 1998

2

Synthetic Oleanane and Ursane Triterpenoids with Modified Rings A and C: A Series of Highly Active Inhibitors of Nitric Oxide Production in Mouse Macrophages †

Honda, Tadashi, Rounds, BarbieAnn V., Bore, Lothar, Finlay, Heather J., Favaloro,, Frank G., Suh, Nanjoo, Wang, Yongping, Sporn, Michael B., Gribble, Gordon W.

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 226 KB

english, 2000

3

ChemInform Abstract: Novel Synthetic Oleanane Triterpenoids: A Series of Highly Active Inhibitors of Nitric Oxide Production in Mouse Macrophages.

Tadashi Honda, BarbieAnn V. Rounds, Lothar Bore, Frank G. Favaloro Jr., Gordon W. Gribble, Nanjoo Suh, Yongping Wang, Michael B. Sporn

Journal:

Year:

2000

File:

PDF, 31 KB

2000

4

ChemInform Abstract: Novel Synthetic Oleanane and Ursane Triterpenoids with Various Enone Functionalities in Ring A as Inhibitors of Nitric Oxide Production in Mouse Macrophages.

Tadashi Honda, Gordon W. Gribble, Nanjoo Suh, Heather J. Finlay, BarbieAnn V. Rounds, Lothar Bore, Frank G. Favaloro Jr., Yongping Wang, Michael B. Sporn

Journal:

Year:

2000

File:

PDF, 33 KB

2000

5

ChemInform Abstract: Synthesis of β-Boswellic Acid Analogues with a Carboxyl Group at C-17 Isolated from the Bark of Schefflera octophylla.

Lothar Bore, Tadashi Honda, Gordon W. Gribble

Journal:

Year:

2001

File:

PDF, 36 KB

2001

6

ChemInform Abstract: A Novel Dicyanotriterpenoid, 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile, Active at Picomolar Concentrations for Inhibition of Nitric Oxide Production

Tadashi Honda, Yukiko Honda, Frank G. Favaloro Jr., Gordon W. Gribble, Nanjoo Suh, Andrew E. Place, Mara H. Rendi, Michael B. Sporn

Journal:

Year:

2002

File:

PDF, 27 KB

2002

7

Design and Synthesis of Tricyclic Compounds with Enone Functionalities in Ring A and C: A Novel Class of Highly Active Inhibitors of Nitric Oxide Production in Mouse Macrophages

Frank G. Favaloro Jr., Tadashi Honda, Yukiko Honda, Gordon W. Gribble, Nanjoo Suh, Renee Risingsong, Michael B. Sporn

Journal:

Year:

2003

File:

PDF, 79 KB

2003

8

Efficient Synthesis of (-)- and (+)-Tricyclic Compounds with Enone Functionalities in Rings A and C. A Novel Class of Orally Active Antiinflammatory and Cancer Chemopreventive Agents.

Tadashi Honda, Frank G. Jr. Favaloro, Tomasz Janosik, Yukiko Honda, Nanjoo Suh, Michael B. Sporn, Gordon W. Gribble

Journal:

Year:

2004

File:

PDF, 68 KB

2004

9

Platforms and networks in triterpenoid pharmacology

Michael B. Sporn, Karen Liby, Mark M. Yore, Nanjoo Suh, Adriana Albini, Tadashi Honda, Chitra Sundararajan, Gordon W. Gribble

Journal:

Drug Development Research

Year:

2007

Language:

english

File:

PDF, 178 KB

english, 2007

10

Serological responses following influenza A H1N1 2009 infection in adults

Sophia Tan, David L. Gordon, Yoshikazu Honda-Okubo, Nikolai Petrovsky, Peter Phillips, Sandra Huddleston, Tania A. Sadlon

Journal:

Journal of Infection

Year:

2011

Language:

english

File:

PDF, 492 KB

english, 2011

11

Lessons learned from the ITER safety approach for future fusion facilities

C. Gordon, H.-W. Bartels, T. Honda, M. Iseli, J. Raeder, L. Topilski, K. Moshonas, N. Taylor

Journal:

Fusion Engineering and Design

Year:

2001

Language:

english

File:

PDF, 81 KB

english, 2001

12

ITER reference accidents

H.-W. Bartels, A. Poucet, G. Cambi, C. Gordon, M. Gaeta, W. Gulden, T. Honda, M. Iseli, H. Jahn, J. Koonce, O. Kveton, B. Merrill, N. Mitchell, R.L. Moore, D. Petti, S. Polkinghorne, M.T. Porfiri, J.

Journal:

Fusion Engineering and Design

Year:

1998

Language:

english

File:

PDF, 131 KB

english, 1998

13

New enone derivatives of oleanolic acid and ursolic acid as inhibitors of nitric oxide production in mouse macrophages

Tadashi Honda, Heather J. Finlay, Gordon W. Gribble, Nanjoo Suh, Michael B. Sporn

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 286 KB

english, 1997

14

Novel A-ring cleaved analogs of oleanolic and ursolic acids which affect growth regulation in NRP.152 prostate cells

Heather J. Finlay, Tadashi Honda, Gordon W. Gribble, David Danielpour, Nicole E. Benoit, Nanjoo Suh, Charlotte Williams, Michael B. Sporn

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 181 KB

english, 1997

15

Novel synthetic oleanane triterpenoids: A series of highly active inhibitors of nitric oxide production in mouse macrophages

Ta-i Honda, BarbieAnn V. Rounds, Lothar Bore, Frank G. Favaloro Jr., Gordon W. Gribble, Nanjoo Suh, Yongping Wang, Michael B. Sporn

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 313 KB

english, 1999

16

Studies on the reactivity of CDDO, a promising new chemopreventive and chemotherapeutic agent: implications for a molecular mechanism of action

Robin D. Couch, R. Greg Browning, Tadashi Honda, Gordon W. Gribble, Dennis L. Wright, Michael B. Sporn, Amy C. Anderson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 234 KB

english, 2005

17

Design, synthesis, and anti-inflammatory activity both in vitro and in vivo of new betulinic acid analogues having an enone functionality in ring A

Tadashi Honda, Karen T. Liby, Xiaobo Su, Chitra Sundararajan, Yukiko Honda, Nanjoo Suh, Renee Risingsong, Charlotte R. Williams, Darlene B. Royce, Michael B. Sporn, Gordon W. Gribble

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 192 KB

english, 2006

18

A novel dicyanotriterpenoid, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile, active at picomolar concentrations for inhibition of nitric oxide production

Tadashi Honda, Yukiko Honda, Frank G. Favaloro Jr., Gordon W. Gribble, Nanjoo Suh, Andrew E. Place, Mara H. Rendi, Michael B. Sporn

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 126 KB

english, 2002

19

Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

Takaoka, Akinori, Yanai, Hideyuki, Kondo, Seiji, Duncan, Gordon, Negishi, Hideo, Mizutani, Tatsuaki, Kano, Shin-ichi, Honda, Kenya, Ohba, Yusuke, Mak, Tak W.

Journal:

Year:

2005

Language:

english

File:

PDF, 559 KB

english, 2005

20

The Development, Ultrastructural Cytology, and Molecular Phylogeny of the Basal Oomycete Eurychasma dicksonii, Infecting the Filamentous Phaeophyte Algae Ectocarpus siliculosus and Pylaiella littoralis

Satoshi Sekimoto, Gordon W. Beakes, Claire M.M. Gachon, Dieter G. Müller, Frithjof C. Küpper, Daiske Honda

Journal:

Year:

2008

Language:

english

File:

PDF, 3.34 MB

english, 2008

21

Partial Synthesis of Krukovines A and B, Triterpene Ketones Isolated from the Brazilian Medicinal Plant Maytenus krukovii

Honda, Tadashi, Finlay, Heather J., Gribble, Gordon W.

Journal:

Journal of Natural Products

Year:

1997

Language:

english

File:

PDF, 124 KB

english, 1997

22

A dicyanotriterpenoid induces cytoprotective enzymes and reduces multiplicity of skin tumors in UV-irradiated mice

Albena T. Dinkova-Kostova, Stephanie N. Jenkins, Scott L. Wehage, David L. Huso, Andrea L. Benedict, Katherine K. Stephenson, Jed W. Fahey, Hua Liu, Karen T. Liby, Tadashi Honda, Gordon W. Gribble, Mi

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 480 KB

english, 2008

23

Randomized clinical trial of immunogenicity and safety of a recombinant H1N1/2009 pandemic influenza vaccine containing Advax™ polysaccharide adjuvant

David L. Gordon, Dimitar Sajkov, Richard J. Woodman, Yoshikazu Honda-Okubo, Manon M.J. Cox, Susanne Heinzel, Nikolai Petrovsky

Journal:

Year:

2012

Language:

english

File:

PDF, 363 KB

english, 2012

24

Olpidiopsis bostrychiae sp. nov.: an endoparasitic oomycete that infects Bostrychia and other red algae (Rhodophyta)

Sekimoto, Satoshi, Klochkova, Tatyana A., West, John A., Beakes, Gordon W., Honda, Daiske

Journal:

Year:

2009

Language:

english

File:

PDF, 2.74 MB

english, 2009

25

Design, Synthesis, and Biological Evaluation of Biotin Conjugates of 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic Acid for the Isolation of the Protein Targets

Honda, Tadashi, Janosik, Tomasz, Honda, Yukiko, Han, Jie, Liby, Karen T., Williams, Charlotte R., Couch, Robin D., Anderson, Amy C., Sporn, Michael B., Gribble, Gordon W.

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 268 KB

english, 2004

26

Design and Synthesis of 23,24-Dinoroleanolic Acid Derivatives, Novel Triterpenoid−Steroid Hybrid Molecules

Honda, Tadashi, Gribble, Gordon W.

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 63 KB

english, 1998

27

Novel Synthetic Oleanane and Ursane Triterpenoids with Various Enone Functionalities in Ring A as Inhibitors of Nitric Oxide Production in Mouse Macrophages †

Honda, Tadashi, Gribble, Gordon W., Suh, Nanjoo, Finlay, Heather J., Rounds, BarbieAnn V., Bore, Lothar, Favaloro,, Frank G., Wang, Yongping, Sporn, Michael B.

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 168 KB

english, 2000

28

Efficient synthesis of (?)- and (+)-tricyclic compounds with enone functionalities in rings A and C. A novel class of orally active anti-inflammatory and cancer chemopreventive agents

Honda, Tadashi, Favaloro, Jr., Frank G., Janosik, Tomasz, Honda, Yukiko, Suh, Nanjoo, Sporn, Michael B., Gribble, Gordon W.

Journal:

Organic & Biomolecular Chemistry

Year:

2003

Language:

english

File:

PDF, 208 KB

english, 2003

29

Synthesis of β-Boswellic Acid Analogues with a Carboxyl Group at C-17 Isolated from the Bark of Schefflera o ctophylla

Bore, Lothar, Honda, Tadashi, Gribble, Gordon W.

Journal:

Journal of Organic Chemistry

Year:

2000

Language:

english

File:

PDF, 75 KB

english, 2000

30

Novel Tricyclic Compounds Having Acetylene Groups at C-8a and Cyano Enones in Rings A and C: Highly Potent Anti-inflammatory and Cytoprotective Agents

Honda, Tadashi, Sundararajan, Chitra, Yoshizawa, Hidenori, Su, Xiaobo, Honda, Yukiko, Liby, Karen T., Sporn, Michael B., Gribble, Gordon W.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 119 KB

english, 2007

31

The effects of marijuana use during pregnancy. II. A study in a low-risk home-delivery population

Greenland, Sander, Richwald, Gary A., Honda, Gordon D.

Journal:

Drug and Alcohol Dependence

Year:

1983

Language:

english

File:

PDF, 496 KB

english, 1983

32

Tricyclic Compounds Containing Nonenolizable Cyano Enones. A Novel Class of Highly Potent Anti-Inflammatory and Cytoprotective Agents(79)

Honda, Tadashi, Yoshizawa, Hidenori, Sundararajan, Chitra, David, Emilie, Lajoie, Marc J., Favaloro, Frank G., Janosik, Tomasz, Su, Xiaobo, Honda, Yukiko, Roebuck, Bill D., Gribble, Gordon W.

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 3.14 MB

english, 2011

33

Clinical and Pathological Features of Bacillary Peliosis Hepatis in Association with Human Immunodeficiency Virus Infection

Perkocha, Luke A., Geaghan, Sharon M., Yen, T.S. Benedict, Nishimura, Steven L., Chan, Steven P., Garcia-Kennedy, Richard, Honda, Gordon, Stoloff, Amy C., Klein, Harvey Z., Goldman, Ronald L., Van Met

Journal:

Boston Medical and Surgical Journal

Year:

1990

Language:

english

File:

PDF, 8.65 MB

english, 1990

34

Design and Synthesis of Tricyclic Compounds with Enone Functionalities in Rings A and C: A Novel Class of Highly Active Inhibitors of Nitric Oxide Production in Mouse Macrophages

Favaloro,, Frank G., Honda, Tadashi, Honda, Yukiko, Gribble, Gordon W., Suh, Nanjoo, Risingsong, Renee, Sporn, Michael B.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 102 KB

english, 2002

35

Revision and Confirmation of the Regiochemistry of Isoxazoles Derived from Methyl Oleanonate and Lanost-8-en-3-one. Synthesis of a New Lanostane Triterpenoid with a Cyano-enone Functionality in Ring A

Honda, Yukiko, Honda, Tadashi, Roy, Sujata, Gribble, Gordon W.

Journal:

Journal of Organic Chemistry

Year:

2003

Language:

english

File:

PDF, 62 KB

english, 2003

36

AN EFFICIENT SYNTHESIS OF TRICYCLIC COMPOUNDS, (±)-(4aβ,8aβ,10aα)-1,2,3,4,4a,6,7,8,8a,9,10,10a-DODECAHYDRO-1,1,4a-TRIMETHYL-2-OXOPHENANTHRENE-8a-CARBOXYLIC ACID, ITS METHYL ESTER, AND (±)-(4aβ,8aβ,10aα)-3,4,4a,6,7,8,8a,9,10,10a-DECAHYDRO-8a-HYDROXYMETHYL-1,1,4a-TRIMETHYLPHENANTHREN-2(1 H )-ONE

Honda, Tadashi, Honda, Yukiko, Yoshizawa, Hidenori, Gribble, Gordon W.

Journal:

Organic Preparations and Procedures International

Year:

2005

Language:

english

File:

PDF, 298 KB

english, 2005

37

Study on the Base-Catalyzed Reverse Vinylogous Aldol Reaction of (4aβ,5β)-4,4a,5,6,7,8-Hexahydro- 5-hydroxy-1,4a-dimethylnaphthalen-2(3 H )-one under Robinson Annulation Conditions

Payette, Joshua N., Honda, Tadashi, Yoshizawa, Hidenori, Favaloro, Frank G., Gribble, Gordon W.

Journal:

Journal of Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 96 KB

english, 2006

38

Synthesis of a Novel Dicyano Abietane Analogue: A Potential Antiinflammatory Agent

Honda, Tadashi, Yoshizawa, Hidenori, Sundararajan, Chitra, Gribble, Gordon W.

Journal:

Journal of Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 80 KB

english, 2006

39

Total synthesis of indole and dihydroindole alkaloids. XII. Selective functionalization of various bisindoles. Efficient syntheses of leurosine and related bisindole alkaloid derivatives

Kutney, James P., Balsevich, John, Bokelman, Gordon H., Hibino, Toshihiko, Honda, Toshio, Itoh, Isamu, Ratcliffe, Arnold H., Worth, Brian R.

Journal:

Canadian Journal of Chemistry

Year:

1978

Language:

english

File:

PDF, 573 KB

english, 1978

40

A Synthetic Triterpenoid, 2-Cyano-3,12-dioxooleana-1,9-dien-28-oic Acid (CDDO), Is a Ligand for the Peroxisome Proliferator-Activated Receptor γ

Wang, Yongping, Porter, Weston W., Suh, Nanjoo, Honda, Tadashi, Gribble, Gordon W., Leesnitzer, Lisa M., Plunket, Kelli D., Mangelsdorf, David J., Blanchard, Steven G., Willson, Timothy M., Sporn, Mic

Journal:

Molecular Endocrinology

Year:

2000

Language:

english

File:

PDF, 359 KB

english, 2000

41

SPIE Proceedings [SPIE Optical Data Storage '95 - San Diego, CA (Sunday 2 July 1995)] Optical Data Storage '95 - High-density phase-change optical disk with a Si reflective layer

Okada, Mitsuya, Ohkubo, Shuichi, Ide, Tatsunori, Murahata, Michio, Honda, Hiroko, Matsui, Tsutomu, Knight, Gordon R., Ooki, Hiroshi, Tyan, Yuan-Sheng

Year:

1995

Language:

english

File:

PDF, 363 KB

english, 1995

42

Partial Synthesis of 23-Hydroxyursolic Acid Isolated from Medicinal Plants of the Rubiaceae Family

Bore, Lothar, Honda, Tadashi, Gribble, Gordon

Journal:

Natural Product Letters

Year:

2002

Language:

english

File:

PDF, 92 KB

english, 2002

43

Non-Hodgkin Lymphoma Masquerading as Necrotizing Tracheobronchitis

Sidhu, Baljinder, Honda, Gordon, Balasubramanian, Vijay P.

Journal:

Year:

2010

Language:

english

File:

PDF, 116 KB

english, 2010

44

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans - ()] A3. FELLOW CASE CONFERENCE, FOURTH EDITION - Primary Pulmonary Synovial Sarcoma: Tale Of Two Rare Tumors - Genes Tell The Story

Kandaswamy, Chitra, Channabasaviah, Anitha, Honda, Gordon, Balasubramanian, Vijay

Year:

2010

Language:

english

File:

PDF, 40 KB

english, 2010

45

Response from Kurata, et al

Kurata, John H., Elashoff, Janet D., Haile, Belinda M., Honda, Gordon D.

Journal:

American Journal of Public Health

Year:

1984

Language:

english

File:

PDF, 382 KB

english, 1984

46

Human Phase 1 trial of low-dose inactivated seasonal influenza vaccine formulated with Advax™ delta inulin adjuvant

Gordon, David L., Sajkov, Dimitar, Honda-Okubo, Yoshikazu, Wilks, Samuel H., Aban, Malet, Barr, Ian G., Petrovsky, Nikolai

Journal:

Year:

2016

Language:

english

File:

PDF, 1.45 MB

english, 2016

47

Panblok-H1+advax H1N1/2009pdm vaccine: Insights into rapid development of an delta inulin adjuvanted recombinant pandemic influenza vaccine

Honda-Okubo, Yoshikazu, Rajapaksha, Harinda, Sajkov, Dimitar, Gordon, David, Cox, Manon M.J., Petrovsky, Nikolai

Journal:

Human Vaccines & Immunotherapeutics

Year:

2017

Language:

english

File:

PDF, 2.09 MB

english, 2017

48

Efficacy of influenza vaccine (Fluvax) in cancer patients on treatment: a prospective single arm, open-label study

Ayoola, A., Sukumaran, S., Jain, K., Kumar, R., Gordon, D., Honda-Okubo, Y., Quinn, S., Roy, A., Vatandoust, S., Koczwara, B., Kichenadasse, G., Richards, A., Mead, K., Karapetis, C.

Journal:

Supportive Care in Cancer

Year:

2020

File:

PDF, 377 KB

2020

49

Hospitalization and Mortality Rates for Peptic Ulcers: A Comparison of a Large Health Maintenance Organization and United States Data

Kurata, John H., Honda, Gordon D., Frankl, Harold

Journal:

Gastroenterology

Year:

1982

File:

PDF, 906 KB

1982

50

Efficacy of Influenza Vaccine (FLUVAX) in Patients Undergoing Chemotherapy

Kumar, R., Gordon, D., Karapetis, C.S., Koczwara, B., Kichenadasse, G., Dua, D., Takhar, H., Jain, K., Honda-Okubo, Y., Sukumaran, S.

Journal:

Annals of Oncology

Year:

2012

File:

PDF, 66 KB

2012